Ultrasound can have either destructive or constructive effects to cells depending on the sonication parameters employed.
Cell Disintegration under intense sonication enzymes or proteins can be released from cells or subcellular organelles as a result of cell disintegration. In this case, the compound to be dissolved into a solvent is enclosed in an insoluble structure. In order to extract it, the cell membrane must be destructed. Cell disruption is a sensitive process, because the cell wall’s capability to withstand high osmotic pressure inside.
Good control of the cell disruption is required, to avoid an unhindered release of all intracellular products including cell debris and nucleic acids, or product denaturation.
Ultrasonication serves as a well-controllable means for cell disintegration. For this, the mechanical effects of ultrasound provide faster and more complete penetration of solvent into cellular materials and improve mass transfer.
Ultrasound achieves greater penetration of a solvent into a plant tissue and improves the mass transfer. Ultrasonic waves generating cavitation disrupt cell walls and facilitate the release of matrix components.
Amplitude/power adjustment range
Volume of reactor
Ultrasonic device + Digital Generator
Stainless steel reactor, Remote communication interface, flow meter